PTPN23

PTPN23
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3RAU, 5CRV, 5CRU
Identifiers
Aliases	PTPN23, HD-PTP, HDPTP, PTP-TD14, protein tyrosine phosphatase, non-receptor type 23, protein tyrosine phosphatase non-receptor type 23, NEDBASS
External IDs	OMIM: 606584; MGI: 2144837; HomoloGene: 135706; GeneCards: PTPN23; OMA:PTPN23 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	47,413,435 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	110,237,281 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; pituitary gland; ; skin of arm; ; anterior pituitary; ; right hemisphere of cerebellum; ; right lobe of thyroid gland; ; stromal cell of endometrium; ; left lobe of thyroid gland; ; gastrocnemius muscle; ; canal of the cervix;
	Top expressed in
	internal carotid artery; ; ventricular zone; ; external carotid artery; ; yolk sac; ; granulocyte; ; neural layer of retina; ; superior frontal gyrus; ; tail of embryo; ; primary visual cortex; ; genital tubercle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	phosphoprotein phosphatase activity; phosphatase activity; protein binding; protein tyrosine phosphatase activity; protein kinase binding; hydrolase activity;
Cellular component	cytoplasm; ciliary basal body; endosome; cell projection; cilium; nucleoplasm; early endosome; extracellular exosome; cytoskeleton; cytoplasmic vesicle; nucleus; nuclear body; cytosol;
Biological process	positive regulation of homophilic cell adhesion; cilium assembly; regulation of cell migration; protein dephosphorylation; positive regulation of adherens junction organization; cell projection organization; protein transport; positive regulation of early endosome to late endosome transport; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; negative regulation of epithelial cell migration; dephosphorylation; peptidyl-tyrosine dephosphorylation; early endosome to late endosome transport; positive regulation of Wnt protein secretion; transport; endocytic recycling; cellular response to cytokine stimulus;
	Sources:Amigo / QuickGO
Orthologs
	25930
	104831
	ENSG00000076201
	ENSMUSG00000036057
	Q9H3S7
	Q6PB44
	NM_001304482; NM_015466
	NM_001081043
	NP_001291411; NP_056281
	NP_001074512
	Wikidata
View/Edit Human	View/Edit Mouse

Tyrosine-protein phosphatase non-receptor type 23 is an enzyme that in humans is encoded by the PTPN23 gene.