PTF1A

PTF1A
Identifiers
Aliases	PTF1A, PACA, PAGEN2, PTF1-p48, bHLHa29, pancreas specific transcription factor, 1a, p48, pancreas associated transcription factor 1a
External IDs	OMIM: 607194; MGI: 1328312; HomoloGene: 10304; GeneCards: PTF1A; OMA:PTF1A - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	23,194,245 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	19,452,312 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; islet of Langerhans; ; gonad; ; body of stomach; ; right testis; ; left testis; ; Brodmann area 9; ; fundus; ; putamen; ; nucleus accumbens;
	Top expressed in
	pyloric antrum; ; urethra; ; female urethra; ; male urethra; ; rhombic lip; ; gray matter layer of cerebellum; ; medial ganglionic eminence; ; epithelium of stomach; ; pancreatic acinus; ; islet of Langerhans;
	More reference expression data
	n/a
Gene ontology
Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding; sequence-specific DNA binding; protein dimerization activity; DNA-binding transcription activator activity, RNA polymerase II-specific; chromatin binding; E-box binding; DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	intracellular anatomical structure; nucleus; cytoplasm; transcription regulator complex;
Biological process	cell differentiation; cell fate commitment; hindbrain development; transcription by RNA polymerase II; cerebellum development; transcription, DNA-templated; nervous system development; generation of neurons; multicellular organism development; positive regulation of transcription, DNA-templated; retina morphogenesis in camera-type eye; retinoic acid receptor signaling pathway; tissue development; pancreas development; neuron fate commitment; positive regulation of transcription by RNA polymerase II; regulation of neural retina development; exocrine pancreas development; retina layer formation; amacrine cell differentiation; regulation of transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	256297
	19213
	ENSG00000168267
	ENSMUSG00000026735
	Q7RTS3
	Q9QX98
	NM_178161
	NM_018809
	NP_835455
	NP_061279
	Wikidata
View/Edit Human	View/Edit Mouse

Pancreas transcription factor 1 subunit alpha is a protein that in humans is encoded by the PTF1A gene.