PRX (gene)

PRX
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4CMZ
Identifiers
Aliases	PRX, CMT4F, periaxin
External IDs	OMIM: 605725; MGI: 108176; HomoloGene: 76542; GeneCards: PRX; OMA:PRX - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	40,414,793 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	27,219,639 bp
RNA expression pattern
	Top expressed in
	olfactory bulb; ; trigeminal ganglion; ; sural nerve; ; spinal ganglia; ; pancreatic ductal cell; ; right lung; ; upper lobe of left lung; ; triceps brachii muscle; ; glutes; ; right lobe of thyroid gland;
	Top expressed in
	sciatic nerve; ; utricle; ; right lung; ; right lung lobe; ; left lung; ; left lung lobe; ; epithelium of lens; ; ankle; ; vestibular sensory epithelium; ; lumbar spinal ganglion;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; molecular function;
Cellular component	cytoplasm; cell junction; plasma membrane; membrane; nucleus; T-tubule;
Biological process	axon ensheathment; regulation of RNA splicing;
	Sources:Amigo / QuickGO
Orthologs
	57716
	19153
	ENSG00000105227
	ENSMUSG00000053198
	Q9BXM0
	O55103
	NM_020956; NM_181882
	NM_019412; NM_198048
	NP_066007; NP_870998
	NP_062285; NP_932165
	Wikidata
View/Edit Human	View/Edit Mouse

Periaxin is a protein that in humans is encoded by the PRX gene.

The PRX gene encodes L- and S-periaxin, proteins of myelinating Schwann cells, and is mutated in Dejerine–Sottas syndrome (MIM 145900) and Charcot–Marie–Tooth disease type 4F (MIM 145900).[supplied by OMIM]