Naluzotan

Naluzotan
Clinical data

Routes of administration	Oral
ATC code	None
Identifiers
IUPAC name N-(3-{4-[4-(1-cyclohexylmethanesulfonamido)butyl]piperazin-1-yl}phenyl)acetamide
CAS Number	740873-06-7
PubChem CID	11430856
ChemSpider	9605731
UNII	LQ54E5B4EW
CompTox Dashboard (EPA)	DTXSID40995527
Chemical and physical data
Formula	C₂₃H₃₈N₄O₃S
Molar mass	450.64 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(Nc3cccc(N2CCN(CCCCNS(=O)(=O)CC1CCCCC1)CC2)c3)C
InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) Key:SPWZXWDPAWDKQE-UHFFFAOYSA-N
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Naluzotan (INN, USAN; PRX-00023) is a serotonergic drug of the phenylpiperazine class that was under investigation by EPIX Pharmaceuticals Inc for the treatment of generalized anxiety disorder and major depressive disorder. It acts as a selective and potent 5-HT_1A receptor partial agonist, readily stimulating prolactin responses, though it has also been found to bind to and activate the σ receptor.