PRSS22

PRSS22
Identifiers
Aliases	PRSS22, BSSP-4, hBSSP-4, SP001LA, protease, serine 22, serine protease 22
External IDs	OMIM: 609343; MGI: 1918085; HomoloGene: 23344; GeneCards: PRSS22; OMA:PRSS22 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	2,858,170 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	24,217,074 bp
RNA expression pattern
	Top expressed in
	olfactory zone of nasal mucosa; ; minor salivary glands; ; gallbladder; ; body of pancreas; ; right uterine tube; ; prostate; ; tonsil; ; vagina; ; right lobe of thyroid gland; ; left lobe of thyroid gland;
	Top expressed in
	conjunctival fornix; ; lip; ; transitional epithelium of urinary bladder; ; cornea; ; superior cervical ganglion; ; epithelium of lens; ; external carotid artery; ; esophagus; ; internal carotid artery; ; ciliary body;
	More reference expression data
	n/a
Gene ontology
Molecular function	peptidase activity; serine-type endopeptidase activity; hydrolase activity; serine-type peptidase activity;
Cellular component	extracellular region; extrinsic component of plasma membrane; anchored component of plasma membrane;
Biological process	proteolysis;
	Sources:Amigo / QuickGO
Orthologs
	64063
	70835
	ENSG00000005001; ENSG00000282937
	ENSMUSG00000045027
	Q9GZN4
	Q9ER10
	NM_022119
	NM_133731
	NP_071402
	NP_598492
	Wikidata
View/Edit Human	View/Edit Mouse

Brain-specific serine protease 4 (BSSP-4), also known as serine protease 22 or tryptase epsilon, is an enzyme that in humans is encoded by the PRSS22 gene.

This gene encodes a member of the trypsin family of serine proteases. The enzyme is expressed in the airways in a developmentally regulated manner. The gene is part of a cluster of serine protease genes on chromosome 16.