PRKAG2

PRKAG2
Identifiers
Aliases	PRKAG2, AAKG, AAKG2, CMH6, H91620p, WPWS, protein kinase AMP-activated non-catalytic subunit gamma 2
External IDs	OMIM: 602743; MGI: 1336153; HomoloGene: 136125; GeneCards: PRKAG2; OMA:PRKAG2 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	151,877,125 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	25,305,640 bp
RNA expression pattern
	Top expressed in
	right auricle of heart; ; cardiac muscle tissue of right atrium; ; right coronary artery; ; left ventricle; ; left coronary artery; ; popliteal artery; ; tibial arteries; ; gastric mucosa; ; nucleus accumbens; ; apex of heart;
	Top expressed in
	seminiferous tubule; ; atrium; ; spermatid; ; dentate gyrus of hippocampal formation granule cell; ; tail of embryo; ; superior frontal gyrus; ; primary visual cortex; ; atrioventricular valve; ; spermatocyte; ; subiculum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; ADP binding; AMP-activated protein kinase activity; protein kinase activator activity; phosphorylase kinase regulator activity; AMP binding; cAMP-dependent protein kinase regulator activity; cAMP-dependent protein kinase inhibitor activity; ATP binding; protein kinase binding; adenyl ribonucleotide binding;
Cellular component	cytosol; nucleoplasm; nucleotide-activated protein kinase complex; extracellular space;
Biological process	carnitine shuttle; intracellular signal transduction; sterol biosynthetic process; regulation of fatty acid oxidation; negative regulation of protein kinase activity; regulation of glucose import; lipid metabolism; regulation of fatty acid biosynthetic process; fatty acid metabolic process; regulation of glycolytic process; protein phosphorylation; fatty acid biosynthetic process; positive regulation of peptidyl-threonine phosphorylation; regulation of fatty acid metabolic process; ATP biosynthetic process; glycogen metabolic process; regulation of catalytic activity; macroautophagy; positive regulation of protein kinase activity; regulation of signal transduction by p53 class mediator; activation of protein kinase activity; negative regulation of protein serine/threonine kinase activity; regulation of macroautophagy; regulation of protein serine/threonine kinase activity;
	Sources:Amigo / QuickGO
Orthologs
	51422
	108099
	ENSG00000106617
	ENSMUSG00000028944
	Q9UGJ0
	Q91WG5
NM_001040633; NM_001304527; NM_001304531; NM_016203; NM_024429;
	NM_001363698
	NM_001170555; NM_001170556; NM_145401; NM_001310480
NP_001035723; NP_001291456; NP_001291460; NP_057287; NP_077747;
	NP_001350627
	NP_001164026; NP_001164027; NP_001297409; NP_663376
	Wikidata
View/Edit Human	View/Edit Mouse

5'-AMP-activated protein kinase subunit gamma-2 is an enzyme that in humans is encoded by the PRKAG2 gene.