PPP5C

PPP5C
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1A17, 1S95, 1WAO, 2BUG, 3H60, 3H61, 3H62, 3H63, 3H64, 3H66, 3H67, 3H68, 3H69, 4ZX2, 4ZVZ
Identifiers
Aliases	PPP5C, PP5, PPP5, PPT, protein phosphatase 5 catalytic subunit
External IDs	OMIM: 600658; MGI: 102666; HomoloGene: 4550; GeneCards: PPP5C; OMA:PPP5C - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	46,392,981 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	16,761,849 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; ganglionic eminence; ; anterior pituitary; ; ventricular zone; ; right hemisphere of cerebellum; ; apex of heart; ; stromal cell of endometrium; ; right auricle of heart; ; right frontal lobe; ; right adrenal gland;
	Top expressed in
	neural layer of retina; ; yolk sac; ; superior frontal gyrus; ; tail of embryo; ; dentate gyrus of hippocampal formation granule cell; ; cerebellar cortex; ; muscle of thigh; ; gastrula; ; epiblast; ; ventricular zone;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	phosphoprotein phosphatase activity; heat shock protein binding; microtubule binding; ADP binding; protein serine/threonine phosphatase activity; signal transducer activity; metal ion binding; protein binding; RNA binding; identical protein binding; G-protein alpha-subunit binding; hydrolase activity; ATP binding; lipid binding; Hsp90 protein binding;
Cellular component	perikaryon; membrane; intracellular membrane-bounded organelle; plasma membrane; soma; proximal dendrite; neuron projection; nucleus; cell periphery; nucleoplasm; cytoplasm; cytosol;
Biological process	negative regulation of protein phosphorylation; positive regulation of glucocorticoid receptor signaling pathway; protein heterooligomerization; protein dephosphorylation; negative regulation of cell death; cellular response to cadmium ion; transcription, DNA-templated; MAPK cascade; cellular response to DNA damage stimulus; response to morphine; response to lead ion; protein complex oligomerization; positive regulation of I-kappaB kinase/NF-kappaB signaling; cellular response to hydrogen peroxide; negative regulation of neuron death; DNA repair; mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	5536
	19060
	ENSG00000011485
	ENSMUSG00000003099
	P53041
	Q60676
	NM_006247; NM_001204284
	NM_011155
	NP_001191213; NP_006238
	NP_035285
	Wikidata
View/Edit Human	View/Edit Mouse

Serine/threonine-protein phosphatase 5 is an enzyme that in humans is encoded by the PPP5C gene.