Pou class 3 homeobox 3

POU3F3
Identifiers
Aliases	POU3F3, BRN1, OTF8, brain-1, oct-8, POU class 3 homeobox 3, SNIBFIS
External IDs	OMIM: 602480; MGI: 102564; HomoloGene: 68509; GeneCards: POU3F3; OMA:POU3F3 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	104,858,574 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	42,742,336 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; corpus epididymis; ; renal medulla; ; seminal vesicula; ; internal globus pallidus; ; caput epididymis; ; inferior ganglion of vagus nerve; ; postcentral gyrus; ; external globus pallidus;
	Top expressed in
	medial ganglionic eminence; ; ventricular zone; ; globus pallidus; ; Rostral migratory stream; ; medullary collecting duct; ; dorsal tegmental nucleus; ; lower lip; ; ventral tegmental area; ; deep cerebellar nuclei; ; dorsomedial hypothalamic nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	sequence-specific DNA binding; DNA binding; DNA-binding transcription factor activity; HMG box domain binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	regulation of transcription, DNA-templated; kidney development; regulation of transcription by RNA polymerase II; negative regulation of apoptotic process; transcription, DNA-templated; nervous system development; metanephric ascending thin limb development; positive regulation of transcription, DNA-templated; multicellular organism development; central nervous system development; forebrain ventricular zone progenitor cell division; brain development; positive regulation of gene expression; metanephric loop of Henle development; positive regulation of cell population proliferation; negative regulation of transcription, DNA-templated; cerebral cortex radially oriented cell migration; metanephric thick ascending limb development; positive regulation of transcription by RNA polymerase II; metanephric DCT cell differentiation; metanephric macula densa development; excretion; chemical homeostasis;
	Sources:Amigo / QuickGO
Orthologs
	5455
	18993
	ENSG00000198914
	ENSMUSG00000045515
	P20264
	P31361
	NM_006236
	NM_008900
	NP_006227
	NP_032926
	Wikidata
View/Edit Human	View/Edit Mouse

POU class 3 homeobox 3 is a protein that in humans is encoded by the POU3F3 gene.