PLA2R1

PLA2R1
Identifiers
Aliases	PLA2R1, CLEC13C, PLA2-R, PLA2G1R, PLA2IR, PLA2R, phospholipase A2 receptor 1
External IDs	OMIM: 604939; MGI: 102468; HomoloGene: 32016; GeneCards: PLA2R1; OMA:PLA2R1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	160,062,615 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	60,383,652 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; left lobe of thyroid gland; ; Achilles tendon; ; right lobe of thyroid gland; ; right coronary artery; ; popliteal artery; ; tibial arteries; ; olfactory zone of nasal mucosa; ; Descending thoracic aorta; ; skin of leg;
	Top expressed in
	neural layer of retina; ; transitional epithelium of urinary bladder; ; molar; ; olfactory epithelium; ; retinal pigment epithelium; ; decidua; ; pineal gland; ; umbilical cord; ; gastrula; ; uterus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	phospholipase binding; carbohydrate binding; transmembrane signaling receptor activity; signaling receptor activity;
Cellular component	integral component of membrane; extracellular region; cell surface; receptor complex; plasma membrane; membrane; integral component of plasma membrane;
Biological process	cytokine production; positive regulation of DNA damage response, signal transduction by p53 class mediator; endocytosis; positive regulation of arachidonic acid secretion; receptor-mediated endocytosis; oxidative stress-induced premature senescence; reactive oxygen species metabolic process; replicative senescence; signal transduction; negative regulation of phospholipase A2 activity; negative regulation of arachidonic acid secretion;
	Sources:Amigo / QuickGO
Orthologs
	22925
	18779
	ENSG00000153246
	ENSMUSG00000054580
	Q13018
	Q62028
	NM_001007267; NM_001195641; NM_007366
	NM_008867
	NP_001007268; NP_001182570; NP_031392
	NP_032893
	Wikidata
View/Edit Human	View/Edit Mouse

Secretory phospholipase A2 receptor is a protein that in humans is encoded by the PLA2R1 gene.