PITX1

PITX1
Identifiers
Aliases	PITX1, BFT, CCF, LBNBG, POTX, PTX1, paired like homeodomain 1
External IDs	OMIM: 602149; MGI: 107374; HomoloGene: 20584; GeneCards: PITX1; OMA:PITX1 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	135,034,813 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	55,984,005 bp
RNA expression pattern
	Top expressed in
	mucosa of pharynx; ; pituitary gland; ; oral mucosa; ; minor salivary glands; ; anterior pituitary; ; gums; ; gingival epithelium; ; gastric mucosa; ; muscle of thigh; ; olfactory zone of nasal mucosa;
	Top expressed in
	oral mucosa; ; wall of esophagus; ; mucosa of esophagus; ; epithelium of esophagus; ; Rathke's pouch; ; mandibular prominence; ; yolk sac; ; mandible; ; submandibular gland; ; muscle of anterior abdominal wall;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; protein binding; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytoplasm; transcription regulator complex; nucleolus; nucleus;
Biological process	skeletal system development; pituitary gland development; regulation of transcription, DNA-templated; anatomical structure morphogenesis; transcription by RNA polymerase II; hindlimb morphogenesis; transcription, DNA-templated; multicellular organism development; cartilage development; myoblast fate commitment; negative regulation of transcription, DNA-templated; branchiomeric skeletal muscle development; positive regulation of transcription by RNA polymerase II; embryonic hindlimb morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	5307
	18740
	ENSG00000069011
	ENSMUSG00000021506
	P78337
	P70314
	NM_002653
	NM_011097
	NP_002644
	NP_035227
	Wikidata
View/Edit Human	View/Edit Mouse

Paired-like homeodomain 1 is a protein that in humans is encoded by the PITX1 gene.