PHA-57378

PHA-57378
Identifiers
	IUPAC name 2,7,8,9,10,11-hexahydro-1H-azepino[4,5-b][1,4]oxazino[2,3,4-hi]indole;
CAS Number	303798-94-9 ;
PubChem CID	10198481;
ChemSpider	8373981;
Chemical and physical data
Formula	C14H16N2O
Molar mass	228.295 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1(OCC2)=C(N2C3=C4CCNCC3)C4=CC=C1;
	InChI InChI=1S/C14H16N2O/c1-2-11-10-4-6-15-7-5-12(10)16-8-9-17-13(3-1)14(11)16/h1-3,15H,4-9H2; Key:KMVAXNRPZRSLSY-UHFFFAOYSA-N;

PHA-57378 is a drug related to the ibogalogs which acts as an agonist at serotonin 5-HT₂ receptors, having a binding affinity of 4.1 nM at the 5-HT_2A subtype and 4.3 nM at 5-HT_2C. It has anxiolytic effects in animal studies.

Identifiers

IUPAC name 2,7,8,9,10,11-hexahydro-1H-azepino[4,5-b][1,4]oxazino[2,3,4-hi]indole
CAS Number	303798-94-9^Y
PubChem CID	10198481
ChemSpider	8373981
Chemical and physical data
Formula	C₁₄H₁₆N₂O
Molar mass	228.295 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C1(OCC2)=C(N2C3=C4CCNCC3)C4=CC=C1
InChI InChI=1S/C14H16N2O/c1-2-11-10-4-6-15-7-5-12(10)16-8-9-17-13(3-1)14(11)16/h1-3,15H,4-9H2 Key:KMVAXNRPZRSLSY-UHFFFAOYSA-N