PECI (gene)

ECI2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2CQU, 2F6Q, 4U18, 4U19, 4U1A
Identifiers
Aliases	ECI2, ACBD2, DRS-1, DRS1, HCA88, PECI, dJ1013A10.3, enoyl-CoA delta isomerase 2
External IDs	OMIM: 608024; MGI: 1346064; HomoloGene: 38145; GeneCards: ECI2; OMA:ECI2 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	4,135,597 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	35,211,079 bp
RNA expression pattern
	Top expressed in
	right adrenal gland; ; right adrenal cortex; ; right ventricle; ; triceps brachii muscle; ; left adrenal gland; ; biceps brachii; ; Skeletal muscle tissue of biceps brachii; ; glutes; ; left adrenal cortex; ; left ventricle;
	Top expressed in
	saccule; ; otic placode; ; cardiac muscle tissue of left ventricle; ; renal corpuscle; ; otic vesicle; ; interventricular septum; ; proximal tubule; ; hair follicle; ; ventricular zone; ; vestibular sensory epithelium;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	intramolecular oxidoreductase activity, transposing C=C bonds; signaling receptor binding; catalytic activity; isomerase activity; fatty-acyl-CoA binding; dodecenoyl-CoA delta-isomerase activity;
Cellular component	membrane; mitochondrion; intracellular membrane-bounded organelle; nucleoplasm; peroxisomal matrix; peroxisome; cytosol;
Biological process	fatty acid catabolic process; fatty acid beta-oxidation; metabolism; fatty acid beta-oxidation using acyl-CoA oxidase; protein targeting to peroxisome;
	Sources:Amigo / QuickGO
Orthologs
	10455
	23986
	ENSG00000198721
	ENSMUSG00000021417
	O75521
	Q9WUR2
	NM_001166010; NM_006117; NM_206836
	NM_001110331; NM_001110332; NM_011868
	NP_001159482; NP_006108; NP_996667
	NP_001103801; NP_035998
	Wikidata
View/Edit Human	View/Edit Mouse

Peroxisomal 3,2-trans-enoyl-CoA isomerase is an enzyme that in humans is encoded by the PECI gene.

PECI is an auxiliary enzyme that catalyzes an isomerization step required for the beta-oxidation of unsaturated fatty acids.[supplied by OMIM]