PADI4

PADI4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WD8, 1WD9, 1WDA, 2DEW, 2DEX, 2DEY, 2DW5, 3APM, 3APN, 3B1T, 3B1U, 4DKT, 4X8C, 4X8G
Identifiers
Aliases	PADI4, PAD, PAD4, PADI5, PDI4, PDI5, peptidyl arginine deiminase 4
External IDs	OMIM: 605347; MGI: 1338898; HomoloGene: 7883; GeneCards: PADI4; OMA:PADI4 - orthologs
EC number	3.5.3.15
Gene location (Human)
Chr.	Chromosome 1 (human)
End	17,364,004 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	140,501,547 bp
RNA expression pattern
	Top expressed in
	blood; ; bone marrow; ; bone marrow cells; ; monocyte; ; granulocyte; ; spleen; ; upper lobe of left lung; ; testicle; ; right lung; ; gonad;
	Top expressed in
	granulocyte; ; morula; ; lip; ; hair follicle; ; tibiofemoral joint; ; cervix; ; bone marrow; ; otic vesicle; ; embryo; ; blood;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	metal ion binding; arginine deiminase activity; protein binding; hydrolase activity; protein-arginine deiminase activity; calcium ion binding; arginine binding; protein homodimerization activity;
Cellular component	nucleoplasm; nucleus; cytosol; cytoplasm; protein-containing complex;
Biological process	chromatin remodeling; nucleosome assembly; regulation of transcription, DNA-templated; immune system process; transcription, DNA-templated; stem cell population maintenance; innate immune response; chromatin organization; arginine deiminase pathway;
	Sources:Amigo / QuickGO
Orthologs
	23569
	18602
	ENSG00000280908; ENSG00000159339
	ENSMUSG00000025330
	Q9UM07
	Q9Z183
	NM_012387
	NM_011061
	NP_036519
	NP_035191
	Wikidata
View/Edit Human	View/Edit Mouse

Protein-arginine deiminase type-4, is a human protein which in humans is encoded by the PADI4 gene. The protein as an enzyme, specifically protein-arginine deiminase, a type of hydrolase.