Oxyphil cell (parathyroid)

Oxyphil cell
High magnification micrograph of parathyroid gland, stained using H&E stain. The cells with orange/pink staining cytoplasm are oxyphil cells
Details
LocationParathyroid gland
Identifiers
THH3.08.02.5.00005
FMA69084
Anatomical terms of microanatomy

Parathyroid oxyphil cells, also named oncocytes, are one out of the two types of cells found in the parathyroid gland, the other being parathyroid chief cell. Oxyphil cells are only found in a select few number of species and humans are one of them.

These cells can be found in clusters in the center of the section and at the periphery. Oxyphil cells appear at the onset of puberty, but have no known function. It is perceived that oxyphil cells may be derived from chief cells at puberty, as they are not present at birth like chief cells. Oxyphil cells increase in number with age.

Although the terms oncocyte, oxyphil cell, and Hürthle cell are used interchangeably, "Hürthle cell" is used only to indicate cells of thyroid follicular origin.