Oligosaccaryltransferase
| Oligosaccaryltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
nmr structure of yeast oligosaccharyltransferase subunit ost4p | |||||||||
| Identifiers | |||||||||
| Symbol | Ost4 | ||||||||
| Pfam | PF10215 | ||||||||
| InterPro | IPR018943 | ||||||||
| OPM superfamily | 242 | ||||||||
| OPM protein | 2lat | ||||||||
| Membranome | 465 | ||||||||
| |||||||||
In molecular biology, OST4 (Dolichyl-diphosphooligosaccharide—protein glycosyltransferase subunit 4) is a subunit of the oligosaccharyltransferase complex. OST4 is a very short, approximately 30 amino acids, protein found from fungi to vertebrates. It appears to be an integral membrane protein that mediates the en bloc transfer of a pre-assembled high-mannose oligosaccharide onto asparagine residues of nascent polypeptides as they enter the lumen of the rough endoplasmic reticulum.