Nyaicili Boki Raja
| Dona Isabel Nyaicili Boki Raja | |
|---|---|
| Regent of Ternate | |
| Reign | 1545–1546 |
| Predecessor | Hairun |
| Successor | Hairun |
| Died | post 1556 |
| Father | Al-Mansur of Tidore |
| Religion | Islam, Christianity |
Nyaicili Boki Raja (died after 1556) was a Queen of Ternate in Maluku Islands who served as regent of the kingdom in 1545-1546. She was later baptized by the Catholic missionary Francis Xavier and took the name Dona Isabel. Being the daughter, wife, sister and mother of kings, she had a potentially bridge-building function between the competing Malukan spice Sultanates Ternate and Tidore, but was repeatedly sidelined by the brutal policy of early European colonialism in Maluku.