Nicotine replacement therapy
A nicotine patch is applied to the left arm. | |
| Clinical data | |
|---|---|
| Trade names | Nicoderm, Commit, Nicorette, others |
| Other names | NRT |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a601084 |
| License data | |
| Routes of administration | Oral, Inhalation, Transdermal, |
| ATC code | |
| Legal status | |
| Legal status |
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| Pharmacokinetic data | |
| Metabolites | Cotinine |
| Excretion | renal |
| Identifiers | |
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| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| Chemical and physical data | |
| Formula | C10H14N2 |
| Molar mass | 162.236 g·mol−1 |
Nicotine replacement therapy (NRT) is a medically approved way to treat people with tobacco use disorder by taking nicotine through means other than tobacco. It is used to help with quitting smoking or stopping chewing tobacco. It increases the chance of quitting tobacco smoking by about 55%. Often it is used along with other behavioral techniques. NRT has also been used to treat ulcerative colitis. Types of NRT include the adhesive patch, chewing gum, lozenges, nose spray, and inhaler. The use of multiple types of NRT at a time may increase effectiveness.
Common side effects depend on the formulation of nicotine. Common side effects with the gum include nausea, hiccups, and irritation of the mouth. Common side effects with the patch include skin irritation and a dry mouth while the inhaler commonly results in a cough, runny nose, or headaches. Serious risks include nicotine poisoning and continued addiction. They do not appear to increase the risk of heart attacks. There are possible harms to the baby if used during pregnancy. Nicotine replacement therapy works by reducing cravings caused by nicotine addiction.
They were first approved for use in 1984, in the United States. Nicotine replacement products are on the World Health Organization's List of Essential Medicines. They are available as generic medications.