Nicomorphine

Nicomorphine
Clinical data
Other namesMorphine dinicotinate, 3,6-dinicotinoylmorphine
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral, Intravenous, Rectal
ATC code
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.010.326
Chemical and physical data
FormulaC29H25N3O5
Molar mass495.535 g·mol−1
3D model (JSmol)
  • O=C(O[C@H]2\C=C/[C@H]6[C@@H]5N(CC[C@@]61c4c(O[C@H]12)c(OC(=O)c3cccnc3)ccc4C5)C)c7cccnc7
  • InChI=1S/C29H25N3O5/c1-32-13-10-29-20-7-9-23(36-28(34)19-5-3-12-31-16-19)26(29)37-25-22(8-6-17(24(25)29)14-21(20)32)35-27(33)18-4-2-11-30-15-18/h2-9,11-12,15-16,20-21,23,26H,10,13-14H2,1H3/t20-,21+,23-,26-,29-/m0/s1 Y
  • Key:HNDXBGYRMHRUFN-CIVUWBIHSA-N Y
 NY (what is this?)  (verify)

Nicomorphine (Vilan, Subellan, Gevilan, MorZet) is the 3,6-dinicotinate ester of morphine. It is a strong opioid agonist analgesic two to three times as potent as morphine with a side effect profile similar to that of dihydromorphine, morphine, and diamorphine.

Nicomorphine was first synthesized in 1904 and was patented as Vilan by Lannacher Heilmittel G.m.b.H. of Austria in 1957.