NUBP2

Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

ParA/MinD ATPase like
ParA/MinD ATPase like
Identifiers
Symbol	ParA
Pfam	PF10609
InterPro	IPR019591
Pfam
Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

NUBP2
Identifiers
Aliases	NUBP2, CFD1, NBP 2, NUBP1, nucleotide binding protein 2, CIAO6, NUBP iron-sulfur cluster assembly factor 2, cytosolic
External IDs	OMIM: 610779; MGI: 1347072; HomoloGene: 8057; GeneCards: NUBP2; OMA:NUBP2 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	1,789,186 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	24,886,349 bp
RNA expression pattern
	Top expressed in
	thymus; ; right lobe of liver; ; right hemisphere of cerebellum; ; apex of heart; ; muscle of thigh; ; fundus; ; body of pancreas; ; right adrenal gland; ; gastrocnemius muscle; ; left adrenal cortex;
	Top expressed in
	spermatocyte; ; seminiferous tubule; ; spermatid; ; right kidney; ; morula; ; fetal liver hematopoietic progenitor cell; ; yolk sac; ; blastocyst; ; embryo; ; proximal tubule;
	More reference expression data
	n/a
Gene ontology
Molecular function	4 iron, 4 sulfur cluster binding; iron-sulfur cluster binding; protein binding; ATP binding; metal ion binding; nucleotide binding;
Cellular component	cytoplasm; centriole; cell projection; spindle pole centrosome; cilium; cytoskeleton; nucleus; microtubule organizing center; cytosol;
Biological process	cell projection organization; iron-sulfur cluster assembly;
	Sources:Amigo / QuickGO
Orthologs
	10101
	26426
	ENSG00000095906
	ENSMUSG00000039183
	Q9Y5Y2
	Q9R061
	NM_001284501; NM_001284502; NM_012225
	NM_011956; NM_001355396
	NP_001271430; NP_001271431; NP_036357
	NP_036086; NP_001342325
	Wikidata
View/Edit Human	View/Edit Mouse

Nucleotide-binding protein 2 (NBP 2) also known as cytosolic Fe-S cluster assembly factor NUBP2 is a protein that in humans is encoded by the NUBP2 gene.

NUBP2 is a member of the NUBP/MRP gene subfamily of ATP-binding proteins. There are two types in eukaryotes NUBP1 and NUBP2, and one novel human gene that define NBP nucleotide-binding proteins (NUBP/MRP-multidrug resistance-associated protein) in mammalian cells requires the maturation of cytosolic iron-sulfur (Fe/S) proteins as Nubp1 is involved in the formation of extramitochondrial Fe/S proteins the cell division inhibitor MinD is homologous and involve two proteins components of the (FeS) protein assembly machinery closely similar cytosolic soluble P loop NTPase where Nar1 is required for assembly, identified Cfd1p in cytosolic and nuclear Fe/S protein biogenesis in yeast. Nubp proteins NTPase Nbp35p. MinD is homologous to members in MinD of E. coli, a relative of the ParA family.