N-Hydroxysuccinimide

N-Hydroxysuccinimide
Names
	Preferred IUPAC name 1-Hydroxypyrrolidine-2,5-dione
	Other names HOSu, HSI.
Identifiers
CAS Number	6066-82-6 ;
3D model (JSmol)	Interactive image;
ChemSpider	72416 ;
ECHA InfoCard	100.025.456
PubChem CID	80170;
UNII	MJE3791M4T ;
CompTox Dashboard (EPA)	DTXSID7064102 ;
	InChI InChI=1S/C4H5NO3/c6-3-1-2-4(7)5(3)8/h8H,1-2H2 Key: NQTADLQHYWFPDB-UHFFFAOYSA-N ; InChI=1/C4H5NO3/c6-3-1-2-4(7)5(3)8/h8H,1-2H2 Key: NQTADLQHYWFPDB-UHFFFAOYAM;
	SMILES O=C1N(O)C(=O)CC1;
Properties
Chemical formula	C4H5NO3
Molar mass	115.09 g/mol
Appearance	Colourless solid
Melting point	96.3 °C (205.3 °F; 369.4 K)
Related compounds
Related imides	Succinimide; N-Bromosuccinimide
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

N-Hydroxysuccinimide (NHS) is an organic compound with the formula (CH₂CO)₂NOH. It is a white solid that is used as a reagent for preparing active esters in peptide synthesis. It can be synthesized by heating succinic anhydride with hydroxylamine or hydroxylamine hydrochloride.