Muir–Torre syndrome

Muir–Torre syndrome
Other namesMTS
Micrograph of a sebaceous adenoma, as may be seen in Muir–Torre syndrome. H&E stain.
SpecialtyOncology, dermatology, medical genetics 

Muir–Torre syndrome is a rare hereditary, autosomal dominant cancer syndrome: 663  that is thought to be a subtype of HNPCC (Lynch syndrome). Individuals are prone to develop cancers of the colon, genitourinary tract, and skin lesions, such as keratoacanthomas and sebaceous tumors. The genes affected are MLH1, MSH2, and more recently, MSH6, and are involved in DNA mismatch repair.

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