Motile sperm domain containing 2

MOSPD2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WIC
Identifiers
Aliases	MOSPD2, Motile sperm domain containing 2
External IDs	MGI: 1924013; HomoloGene: 22125; GeneCards: MOSPD2; OMA:MOSPD2 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	14,922,327 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	163,763,371 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; corpus callosum; ; inferior ganglion of vagus nerve; ; monocyte; ; C1 segment; ; subthalamic nucleus; ; visceral pleura; ; blood; ; decidua; ; Pons;
	Top expressed in
	parotid gland; ; Epithelium of choroid plexus; ; carotid body; ; ciliary body; ; sciatic nerve; ; iris; ; left lung lobe; ; conjunctival fornix; ; seminal vesicula; ; calvaria;
	More reference expression data
	n/a
Orthologs
	158747
	76763
	ENSG00000130150
	ENSMUSG00000061778
	Q8NHP6
	Q9CWP6
	NM_001177475; NM_152581; NM_001330241
	NM_001290523; NM_001290524; NM_029730
	NP_001170946; NP_001317170; NP_689794
	NP_001277452; NP_001277453; NP_084006
	Wikidata
View/Edit Human	View/Edit Mouse

Motile sperm domain containing 2 is a protein that in humans is encoded by the MOSPD2 gene. It is an endoplasmic reticulum–resident protein involved in membrane contact site formation. Its domain homologous to Major Sperm Protein (MSP domain) is very similar to VAPA/VAPB, so it has been described as the third human member of the VAP protein family.