Mississippi–Ohio Valley League
| Formerly | Illinois State League |
|---|---|
| Classification | Class D (1949–1955) |
| Sport | Minor League Baseball |
| First season | 1949 |
| Ceased | 1955 |
| Replaced by | Midwest League |
| President | Dutch Hoffman (1949–1955) |
| No. of teams | 23 |
| Country | United States of America |
| Most titles | 2 Danville Dans (1951, 1954) Decatur Commodores (1952–1953) |
| Related competitions | Illinois-Indiana-Iowa League |
The Mississippi–Ohio Valley League was a Class D level American minor league baseball league. Evolving from the renamed Illinois State League (1947-1948), the Mississippi–Ohio Valley League operated for seven seasons, from 1949 through 1955. In 1956 the league was renamed the Midwest League, which still exists today.