Minoxidil

Minoxidil
Clinical data


Trade names	Loniten, Rogaine, others
Other names	2,4-Diamino-6-piperidinopyrimidine 3-oxide
AHFS/Drugs.com	Monograph
MedlinePlus	a682608
License data	US DailyMed: Minoxidil
Pregnancy category	AU: C
Routes of administration	By mouth, topical
ATC code	C02DC01 (WHO) D11AX01 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) / S2 UK: General sales list (GSL, OTC) / POM US: OTC / Rx-only
Pharmacokinetic data
Bioavailability	>90%
Metabolism	Primarily liver
Elimination half-life	4.2 h
Excretion	Kidney
Identifiers
IUPAC name 2,6-diamino-4-(piperidin-1-yl)pyrimidine 1-oxide
CAS Number	38304-91-5^Y
PubChem CID	4201
IUPHAR/BPS	4254
DrugBank	DB00350^N
ChemSpider	10438564^Y
UNII	5965120SH1
KEGG	D00418^N
ChEBI	CHEBI:6942^N
ChEMBL	ChEMBL802^N
PDB ligand	MXD (PDBe, RCSB PDB)
CompTox Dashboard (EPA)	DTXSID9040685
ECHA InfoCard	100.048.959
Chemical and physical data
Formula	C₉H₁₅N₅O
Molar mass	209.253 g·mol⁻¹
3D model (JSmol)	Interactive image
Melting point	248 °C (478 °F)
Solubility in water	<1
SMILES Nc1cc(nc(N)[n+]1[O-])N2CCCCC2
InChI InChI=1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6H,1-5,10H2,(H2,11,12)^N Key:ZFMITUMMTDLWHR-UHFFFAOYSA-N^N
^NY (what is this?) (verify)

Minoxidil is a medication used for the treatment of high blood pressure and pattern hair loss. It is an antihypertensive and a vasodilator. It is available as a generic medication by prescription in oral tablet form and over-the-counter as a topical liquid or foam.