Methicillin

Methicillin
INN: Meticillin
Clinical data
Routes of; administration	IV
ATC code	J01CF03 (WHO) QJ51CF03 (WHO);
Pharmacokinetic data
Bioavailability	Not orally absorbed
Metabolism	hepatic, 20–40%
Elimination half-life	25–60 minutes
Excretion	renal
Identifiers
	IUPAC name (2S,5R,6R)-6-(2,6-dimethoxybenzamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;
CAS Number	61-32-5 ;
PubChem CID	6087;
DrugBank	DB01603 ;
ChemSpider	5862 ;
UNII	Q91FH1328A;
ChEMBL	ChEMBL575 ;
CompTox Dashboard (EPA)	DTXSID6023284 ;
ECHA InfoCard	100.000.460
Chemical and physical data
Formula	C17H20N2O6S
Molar mass	380.42 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES OC(=O)[C@@H]2N3C(=O)[C@@H](NC(=O)c1c(OC)cccc1OC)[C@H]3SC2(C)C;
	(what is this?) (verify)

Methicillin (USAN), also known as meticillin (INN), is a narrow-spectrum β-lactam antibiotic of the penicillin class.

Methicillin was discovered in 1960.

Clinical data


Routes of administration	IV
ATC code	J01CF03 (WHO) QJ51CF03 (WHO)
Pharmacokinetic data
Bioavailability	Not orally absorbed
Metabolism	hepatic, 20–40%
Elimination half-life	25–60 minutes
Excretion	renal
Identifiers
IUPAC name (2S,5R,6R)-6-(2,6-dimethoxybenzamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
CAS Number	61-32-5^Y
PubChem CID	6087
DrugBank	DB01603^Y
ChemSpider	5862^N
UNII	Q91FH1328A
ChEMBL	ChEMBL575^N
CompTox Dashboard (EPA)	DTXSID6023284
ECHA InfoCard	100.000.460
Chemical and physical data
Formula	C₁₇H₂₀N₂O₆S
Molar mass	380.42 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES OC(=O)[C@@H]2N3C(=O)[C@@H](NC(=O)c1c(OC)cccc1OC)[C@H]3SC2(C)C
^NY (what is this?) (verify)