Melanin-concentrating hormone
| Melanin-concentrating hormone | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | PMCH | ||||||
| CAS number | |||||||
| NCBI gene | 5367 | ||||||
| HGNC | 9109 | ||||||
| OMIM | 176795 | ||||||
| RefSeq | NM_002674 | ||||||
| UniProt | P20382 | ||||||
| Other data | |||||||
| Locus | Chr. 12 q23.2 | ||||||
| |||||||
Melanin-concentrating hormone (MCH), also known as pro-melanin stimulating hormone (PMCH), is a cyclic 19-amino acid orexigenic hypothalamic peptide originally isolated from the pituitary gland of teleost fish, where it controls skin pigmentation. In mammals it is involved in the regulation of feeding behavior, mood, sleep-wake cycle and energy balance.