MYL6

MYL6
Identifiers
Aliases	MYL6, ESMLC, LC17, LC17-GI, LC17-NM, LC17A, LC17B, MLC-3, MLC1SM, MLC3NM, MLC3SM, myosin light chain 6
External IDs	OMIM: 609931; MGI: 109318; HomoloGene: 69080; GeneCards: MYL6; OMA:MYL6 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	56,163,496 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	128,330,014 bp
RNA expression pattern
	Top expressed in
	muscle layer of sigmoid colon; ; popliteal artery; ; tibial arteries; ; left coronary artery; ; right coronary artery; ; ascending aorta; ; Descending thoracic aorta; ; mucosa of transverse colon; ; gastric mucosa; ; body of uterus;
	Top expressed in
	granulocyte; ; dentate gyrus of hippocampal formation granule cell; ; right kidney; ; lip; ; superior frontal gyrus; ; yolk sac; ; neural layer of retina; ; ventricular zone; ; primary visual cortex; ; spermatocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; structural constituent of muscle; cytoskeletal motor activity; protein binding;
Cellular component	vesicle; cytosol; unconventional myosin complex; extracellular exosome; membrane; brush border; myosin complex; extracellular matrix;
Biological process	muscle contraction; skeletal muscle tissue development; muscle filament sliding;
	Sources:Amigo / QuickGO
Orthologs
	4637
	17904
	ENSG00000092841
	ENSMUSG00000090841
	P60660
	Q60605
	NM_079425; NM_021019; NM_079423
	NM_010860; NM_001317217; NM_001317218; NM_001317219; NM_001317220
	NP_066299; NP_524147
	NP_001304146; NP_001304147; NP_001304148; NP_001304149; NP_034990
	Wikidata
View/Edit Human	View/Edit Mouse

Myosin light polypeptide 6 is a protein that in humans is encoded by the MYL6 gene.

Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain that is expressed in smooth muscle and non-muscle tissues. Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene.