Metallothionein 2A

MT2A
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	1MHU, 2MHU
Identifiers
Aliases	MT2A, MT2, Metallothionein 2A, MT-II, MT-2
External IDs	OMIM: 156360; HomoloGene: 136536; GeneCards: MT2A; OMA:MT2A - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	56,609,497 bp
RNA expression pattern
	Top expressed in
	pericardium; ; right lobe of liver; ; olfactory bulb; ; mucosa of transverse colon; ; left uterine tube; ; external globus pallidus; ; cartilage tissue; ; right lobe of thyroid gland; ; upper lobe of left lung; ; Region I of hippocampus proper;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; metal ion binding; zinc ion binding;
Cellular component	cytoplasm; perinuclear region of cytoplasm; cytosol; nucleus;
Biological process	response to metal ion; cellular response to interleukin-3; cellular response to erythropoietin; negative regulation of growth; cellular response to zinc ion; interferon-gamma-mediated signaling pathway; cellular copper ion homeostasis; cellular zinc ion homeostasis; detoxification of copper ion; cellular response to cadmium ion; cellular response to copper ion; nitric oxide mediated signal transduction; response to bacterium;
	Sources:Amigo / QuickGO
Orthologs
	4502
	n/a
	ENSG00000125148
	n/a
	P02795
	n/a
	NM_005953
	n/a
	NP_005944
	n/a
	Wikidata
View/Edit Human

Metallothionein-2 is a metallothionein protein that in humans is encoded by the MT2A gene.

The single-nucleotide polymorphism rs28366003 which substitutes guanine for adenine in MT2A is associated with certain cancers and some chronic diseases.