MLANA

MLANA
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2GT9, 2GTW, 2GTZ, 2GUO, 3HG1, 3L6F, 3MRO, 3MRP, 3MRQ, 3QDM, 3QEQ, 3QFD, 4EUP, 4JFF, 4L3E, 4QOK, 4WJ5, 5E9D
Identifiers
Aliases	MLANA, MART-1, MART1, melan-A
External IDs	OMIM: 605513; MGI: 108454; HomoloGene: 4026; GeneCards: MLANA; OMA:MLANA - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	5,910,606 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	29,686,034 bp
RNA expression pattern
	Top expressed in
	skin of thigh; ; retinal pigment epithelium; ; skin of abdomen; ; testicle; ; skin of arm; ; gonad; ; vulva; ; skin of hip; ; human penis; ; monocyte;
	Top expressed in
	iris; ; ciliary body; ; hair follicle; ; stria vascularis; ; skin of abdomen; ; retinal pigment epithelium; ; embryo; ; epithelium of lens; ; embryo; ; skin of back;
	More reference expression data
	; ;
	More reference expression data
Orthologs
	2315
	77836
	ENSG00000120215
	ENSMUSG00000024806
	Q16655
	Q2TA50
	NM_005511
	NM_029993
	NP_005502
	NP_084269
	Wikidata
View/Edit Human	View/Edit Mouse

Protein melan-A also known as melanoma antigen recognized by T cells 1 or MART-1 is a protein that in humans is encoded by the MLANA or "MALENA" gene. A fragment of the protein, usually consisting of the nine amino acids 27 to 35, is bound by MHC class I complexes which present it to T cells of the immune system. These complexes can be found on the surface of melanoma cells. Decameric peptides (26-35) are being investigated as cancer vaccines.