MIB2 (gene)

MIB2
Identifiers
Aliases	MIB2, ZZANK1, ZZZ5, mindbomb E3 ubiquitin protein ligase 2, MIB E3 ubiquitin protein ligase 2
External IDs	OMIM: 611141; MGI: 2679684; HomoloGene: 16062; GeneCards: MIB2; OMA:MIB2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	1,630,605 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	155,753,655 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; apex of heart; ; anterior pituitary; ; right ovary; ; left ovary; ; right hemisphere of cerebellum; ; right uterine tube; ; muscle of thigh; ; left uterine tube; ; skin of abdomen;
	Top expressed in
	granulocyte; ; primary visual cortex; ; superior frontal gyrus; ; internal carotid artery; ; external carotid artery; ; cerebellar cortex; ; dentate gyrus of hippocampal formation granule cell; ; subiculum; ; Rostral migratory stream; ; neural layer of retina;
	More reference expression data
	n/a
Gene ontology
Molecular function	signal transducer activity; zinc ion binding; ubiquitin protein ligase activity; metal ion binding; actin binding; protein binding; ubiquitin-protein transferase activity; transferase activity;
Cellular component	cytoplasm; endosome; early endosome; ubiquitin ligase complex; cytosol;
Biological process	Notch signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB signaling; protein ubiquitination; protein polyubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	142678
	76580
	ENSG00000197530
	ENSMUSG00000029060
	Q96AX9
	Q8R516
	NM_001170686; NM_001170687; NM_001170688; NM_001170689; NM_080875
NM_001256107; NM_001256108; NM_001256110; NM_145124; NM_001369161;
	NM_001369162; NM_001369163; NM_001369164; NM_001369165; NM_001369166; NM_001369167; NM_001369168
	NP_001164157; NP_001164158; NP_001164159; NP_001164160; NP_543151
NP_001243036; NP_001243037; NP_660106; NP_001356090; NP_001356091;
	NP_001356092; NP_001356093; NP_001356094; NP_001356095; NP_001356096; NP_001356097
	Wikidata
View/Edit Human	View/Edit Mouse

E3 ubiquitin-protein ligase MIB2 is an enzyme that in humans is encoded by the MIB2 gene.