MEP1A

MEP1A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1IAF
Identifiers
Aliases	MEP1A, PPHA, meprin A subunit alpha
External IDs	OMIM: 600388; MGI: 96963; HomoloGene: 31323; GeneCards: MEP1A; OMA:MEP1A - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	46,839,778 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	43,813,703 bp
RNA expression pattern
	Top expressed in
	mucosa of ileum; ; jejunal mucosa; ; mucosa of colon; ; mucosa of sigmoid colon; ; rectum; ; mucosa of transverse colon; ; duodenum; ; testicle; ; appendix; ; amniotic fluid;
	Top expressed in
	right kidney; ; ileum; ; proximal tubule; ; human kidney; ; intestinal villus; ; epithelium of small intestine; ; left colon; ; jejunum; ; renal pelvis; ; migratory enteric neural crest cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	zinc ion binding; peptidase activity; metalloendopeptidase activity; protein binding; hydrolase activity; metallopeptidase activity; metal ion binding;
Cellular component	integral component of membrane; meprin A complex; integral component of plasma membrane; extracellular exosome; membrane; extracellular space;
Biological process	digestion; proteolysis;
	Sources:Amigo / QuickGO
Orthologs
	4224
	17287
	ENSG00000112818
	ENSMUSG00000023914
	Q16819
	P28825
	NM_005588
	NM_008585
	NP_005579
	NP_032611
	Wikidata
View/Edit Human	View/Edit Mouse

Meprin A subunit alpha also known as endopeptidase-2 or PABA peptide hydrolase is the alpha subunit of the meprin A enzyme that in humans is encoded by the MEP1A gene. The MEP1A locus is on chromosome 6p in humans and on chromosome 17 in mice.