MCRS1

MCRS1
Identifiers
Aliases	MCRS1, ICP22BP, INO80Q, MCRS2, MSP58, P78, microspherule protein 1
External IDs	OMIM: 609504; MGI: 1858420; HomoloGene: 4622; GeneCards: MCRS1; OMA:MCRS1 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	49,568,145 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	99,149,842 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; granulocyte; ; left ventricle; ; right auricle of heart; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; mucosa of transverse colon; ; right frontal lobe; ; body of stomach; ; left testis;
	Top expressed in
	Mesencephalon; ; neural tube; ; ganglionic eminence; ; spermatocyte; ; ventricular zone; ; epiblast; ; spermatid; ; neural layer of retina; ; limb; ; muscle tissue;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	poly(U) RNA binding; histone acetyltransferase activity (H4-K8 specific); histone acetyltransferase activity (H4-K5 specific); poly(G) binding; protein binding; histone acetyltransferase activity (H4-K16 specific); telomerase inhibitor activity; G-quadruplex RNA binding;
Cellular component	nucleoplasm; nucleolus; histone acetyltransferase complex; nucleus; dendrite; cytoplasm; polysome; perikaryon; endoplasmic reticulum; Ino80 complex; MLL1 complex; NSL complex;
Biological process	positive regulation of protein localization to nucleolus; DNA recombination; regulation of transcription, DNA-templated; negative regulation of telomerase activity; transcription, DNA-templated; histone H4-K5 acetylation; cellular response to DNA damage stimulus; negative regulation of telomere maintenance via telomere lengthening; histone H4-K16 acetylation; histone H4-K8 acetylation; DNA repair; protein deubiquitination; chromatin organization; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	10445
	51812
	ENSG00000187778
	ENSMUSG00000037570
	Q96EZ8
	Q99L90
	NM_001012300; NM_001278341; NM_006337
	NM_001164156; NM_016766
	NP_001012300; NP_001265270; NP_006328
	NP_001157628; NP_058046
	Wikidata
View/Edit Human	View/Edit Mouse

Microspherule protein 1 is a protein that in humans is encoded by the MCRS1 gene.