MBD4

MBD4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2MOE, 3IHO, 4DK9, 4E9E, 4E9F, 4E9G, 4E9H, 4EA4, 4EA5, 4LG7, 4OFA, 4OFE, 4OFH, 5CHZ
Identifiers
Aliases	MBD4, MED1, methyl-CpG binding domain 4, DNA glycosylase
External IDs	OMIM: 603574; MGI: 1333850; HomoloGene: 2916; GeneCards: MBD4; OMA:MBD4 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	129,440,179 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	115,830,332 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; pylorus; ; visceral pleura; ; trabecular bone; ; caput epididymis; ; epithelium of nasopharynx; ; optic nerve; ; cardia; ; renal medulla; ; corpus epididymis;
	Top expressed in
	lumbar spinal ganglion; ; epithelium of male urethra; ; genital tubercle; ; tail of embryo; ; vagina; ; Rostral migratory stream; ; ejaculatory duct; ; pelvic part of vagina; ; epiblast; ; embryo;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; satellite DNA binding; endodeoxyribonuclease activity; protein binding; catalytic activity; hydrolase activity; pyrimidine-specific mismatch base pair DNA N-glycosylase activity; DNA N-glycosylase activity;
Cellular component	chromatin; nucleus; nucleoplasm; nuclear speck;
Biological process	response to estradiol; depyrimidination; DNA repair; cellular response to DNA damage stimulus; response to radiation;
	Sources:Amigo / QuickGO
Orthologs
	8930
	17193
	ENSG00000129071
	ENSMUSG00000030322
	O95243
	Q9Z2D7
	NM_001276270; NM_001276271; NM_001276272; NM_001276273; NM_003925
	NM_010774
	NP_001263199; NP_001263200; NP_001263201; NP_001263202; NP_003916
	NP_034904
	Wikidata
View/Edit Human	View/Edit Mouse

Methyl-CpG-binding domain protein 4 is a protein that in humans is encoded by the MBD4 gene.