MASP2 (protein)

MASP2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4FXG, 1Q3X, 1SZB, 1ZJK, 3TVJ
Identifiers
Aliases	MASP2, MAP19, MASP-2, MASP1P1, sMAP, mannan binding lectin serine peptidase 2, Mannan-binding lectin serine protease 2, MBL associated serine protease 2, MAP-2
External IDs	OMIM: 605102; MGI: 1330832; HomoloGene: 4819; GeneCards: MASP2; OMA:MASP2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	11,047,239 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	148,699,956 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; pancreatic ductal cell; ; left uterine tube; ; monocyte; ; muscle of leg; ; gastrocnemius muscle; ; skin of leg; ; tibial nerve;
	Top expressed in
	left lobe of liver; ; gallbladder; ; superior surface of tongue; ; morula; ; superior frontal gyrus; ; primary visual cortex; ; muscle of thigh; ; ascending aorta; ; embryo; ; lumbar spinal ganglion;
	More reference expression data
	n/a
Gene ontology
Molecular function	calcium ion binding; peptidase activity; serine-type peptidase activity; protein binding; hydrolase activity; calcium-dependent protein binding; metal ion binding; complement component C4b binding; serine-type endopeptidase activity;
Cellular component	extracellular region; extracellular exosome; extracellular space;
Biological process	complement activation, lectin pathway; proteolysis; complement activation, classical pathway; immune system process; innate immune response; complement activation;
	Sources:Amigo / QuickGO
Orthologs
	10747
	17175
	ENSG00000009724
	ENSMUSG00000028979
	O00187
	Q91WP0
	NM_139208; NM_006610
	NM_001003893; NM_010767
	NP_006601; NP_631947
	NP_001003893; NP_034897
	Wikidata
View/Edit Human	View/Edit Mouse

Mannan-binding lectin serine protease 2 also known as mannose-binding protein-associated serine protease 2 (MASP-2) is an enzyme that in humans is encoded by the MASP2 gene.