MARK2

MARK2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3IEC, 5EAK
Identifiers
Aliases	MARK2, EMK-1, EMK1, PAR-1, Par-1b, Par1b, microtubule affinity regulating kinase 2
External IDs	OMIM: 600526; MGI: 99638; HomoloGene: 69013; GeneCards: MARK2; OMA:MARK2 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	63,911,020 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	7,319,225 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; skin of abdomen; ; mucosa of transverse colon; ; skin of leg; ; monocyte; ; rectum; ; minor salivary glands; ; islet of Langerhans; ; right hemisphere of cerebellum; ; apex of heart;
	Top expressed in
	Ileal epithelium; ; zygote; ; corneal stroma; ; superior surface of tongue; ; CA3 field; ; lactiferous gland; ; cardiac muscle tissue of left ventricle; ; granulocyte; ; plantaris muscle; ; secondary oocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; protein kinase activator activity; metal ion binding; kinase activity; protein serine/threonine kinase activity; tau-protein kinase activity; protein binding; ATP binding; magnesium ion binding; lipid binding; RNA binding; cadherin binding; tau protein binding;
Cellular component	microtubule bundle; cytoplasm; lateral plasma membrane; membrane; plasma membrane; mitochondrion; actin filament; cytoskeleton; nucleoplasm; dendrite; cell projection;
Biological process	cell differentiation; intracellular signal transduction; phosphorylation; mitochondrion localization; neuron migration; Wnt signaling pathway; regulation of axonogenesis; multicellular organism development; protein phosphorylation; autophagy of mitochondrion; establishment or maintenance of epithelial cell apical/basal polarity; positive regulation of neuron projection development; protein autophosphorylation; peptidyl-threonine phosphorylation; activation of protein kinase activity; regulation of cytoskeleton organization; establishment of cell polarity; microtubule cytoskeleton organization; peptidyl-serine phosphorylation; axon development; regulation of microtubule cytoskeleton organization; establishment or maintenance of cell polarity regulating cell shape; regulation of microtubule binding;
	Sources:Amigo / QuickGO
Orthologs
	2011
	13728
	ENSG00000072518
	ENSMUSG00000024969
	Q7KZI7
	Q05512
	NM_001039469; NM_001163296; NM_001163297; NM_004954; NM_017490
	NM_001080388; NM_001080389; NM_001080390; NM_007928
	NP_001034558; NP_001156768; NP_001156769; NP_004945; NP_059672
	NP_001073857; NP_001073858; NP_001073859; NP_031954
	Wikidata
View/Edit Human	View/Edit Mouse

Serine/threonine-protein kinase MARK2 is an enzyme that in humans is encoded by the MARK2 gene.