MAPKAPK3

MAPKAPK3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3FHR, 3FXW, 3R1N, 3SHE
Identifiers
Aliases	MAPKAPK3, 3PK, MAPKAP-K3, MAPKAP3, MAPKAPK-3, MK-3, mitogen-activated protein kinase-activated protein kinase 3, MDPT3, MAPK activated protein kinase 3, MK3
External IDs	OMIM: 602130; MGI: 2143163; HomoloGene: 55836; GeneCards: MAPKAPK3; OMA:MAPKAPK3 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	50,649,291 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	107,167,076 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; left ventricle; ; body of tongue; ; gastrocnemius muscle; ; myocardium of left ventricle; ; monocyte; ; right auricle of heart; ; right ventricle; ; granulocyte; ; tibialis anterior muscle;
	Top expressed in
	hair follicle; ; granulocyte; ; conjunctival fornix; ; lip; ; skin of external ear; ; Paneth cell; ; semi-lunar valve; ; temporal muscle; ; esophagus; ; aortic valve;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; calcium-dependent protein serine/threonine kinase activity; calmodulin binding; kinase activity; protein binding; calmodulin-dependent protein kinase activity; ATP binding; MAP kinase kinase activity; protein serine/threonine kinase activity; mitogen-activated protein kinase binding;
Cellular component	cytoplasm; cytosol; nucleoplasm; nucleus;
Biological process	response to cytokine; phosphorylation; protein phosphorylation; cell surface receptor signaling pathway; response to lipopolysaccharide; vascular endothelial growth factor receptor signaling pathway; macropinocytosis; peptidyl-serine phosphorylation; protein autophosphorylation; signal transduction; toll-like receptor signaling pathway; MAPK cascade; intracellular signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	7867
	102626
	ENSG00000114738
	ENSMUSG00000032577
	Q16644
	Q3UMW7
	NM_001243925; NM_001243926; NM_004635
	NM_178907; NM_001316691
	NP_001230854; NP_001230855; NP_004626
	NP_001303620; NP_849238
	Wikidata
View/Edit Human	View/Edit Mouse

MAP kinase-activated protein kinase 3 is an enzyme that in humans is encoded by the MAPKAPK3 gene.