Lysophosphatidylserine

A lysophosphatidylserine is a lysophospholipid. Various lysophosphatidylserines trigger TLR 2. They can also modulate T cell function via suppression of Interleukin_2 (IL-2) production in CD4 T cells. They can also trigger mast cell degranulation. They interact with three G protein-coupled receptors (GPCRs), LPS1/GPR34, LPS2/P2Y10, and LPS3/GPR174.

A recent study showed that lysophosphatidylserines do not stimulate normal leukocytes. They also enhances glucose transport, lowering blood glucose levels while leaving secretion of insulin unaffected.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.