| Name | Constituency | Notes |
| James Annesley, Lord Annesley | County Waterford | Replace Richard Power who succeeded to a peerage in 1661 |
| Nicholas Bayly | Newry | |
| Henry Bellingham | County Louth | |
| Randal Beresford | Coleraine | |
| Tristram Beresford | County Londonderry | |
| Sir George Bingham | Castlebar | |
| Richard Blayney | County Monaghan | |
| John Blennerhassett | County Kerry | |
| John Blennerhassett | Tralee | |
| Sir George Blundell | Philipstown | |
| Joshua Boyle | Clonakilty | |
| Murrough Boyle | Kilmallock | |
| Richard Boyle | County Cork | Died 1665 and replaced by Roger Boyle. |
| Roger Boyle | County Cork | |
| Edward Brabazon | County Wicklow | Elected in 1666 to replace Folliott Wingfield |
| Sir Thomas Bramhall | Dungannon | |
| Sir Thomas Bramhall | Tuam | Sat for Dungannon | |
| St John Broderick | Kinsale | |
| Sir Allen Broderick | Dungarvan | |
| Richard Bulkeley | Baltinglass | |
| Thomas Burdett | Carlow | |
| Sir Francis Butler | Old Leighlin | |
| Lord John Butler | Dublin University | |
| Stephen Butler | Belturbet | Died and replaced in 1662 by his son Francis Butler |
| John Campbell | Callan | |
| Henry Cary | Fore | Elected 1662 to replace Sir Timothy Tyrrill. Died 1663 and was replaced by John Forrest |
| Thomas Caulfeild | Charlemont | |
| Sir Arthur Chichester | Dungannon | |
| Randolph Clayton | Kinsale | |
| John Cliffe | Taghmon | |
| Sir John Cole | County Fermanagh | |
| Sir Michael Cole | Enniskillen | |
| Sir Robert Cole | Enniskillen | |
| Dudley Colley | Philipstown | |
| Robert Colville | Hillsborough | |
| Edward Cook | Clogher | |
| Charles Coote | County Roscommon | Replaced 1662 by George Lane, 1st Viscount Lanesborough. |
| Sir Peter Courthorpe | Cork City | |
| John Craige | Strabane | |
| Edward Crofton | Lanesborough | |
| Vere Essex Cromwell | County Down | |
| James Cuffe | County Mayo | |
| Sir Thomas Dancer | New Ross | |
| Henry Davys | Belfast | |
| Hercules Davys | Carrickfergus | |
| John Davys | County Antrim | |
| Sir Paul Davys | County Kildare | |
| Sir William Davys | Dublin City | |
| William Davys | County Fermanagh | Died and replaced 1662 by Henry Blennerhassett |
| Arthur Denny | County Kerry | |
| Edward Dering | Lisburn | |
| Carey Dillon | Banagher | |
| William Domville | Antrim Borough | Elected when the constituency was created in 1665 |
| Sir William Domville | County Dublin | Attorney-General for Ireland |
| Matthew Draper | Clogher | |
| Sir John Edgeworth | St Johnstown (Co Longford) | |
| Sir Maurice Eustace jnr | Knocktopher | |
| Sir Maurice Fenton | Fethard (County Tipperary) | |
| Gerald Fitzgerald | Limerick City | |
| John FitzGerald | Dungarvan | |
| Robert Fitzgerald | County Kildare | |
| Sir William Flower | St Canice | |
| Sir Arthur Forbes | County Tyrone | Also elected for Mullingar | |
| Sir Robert Forth | County Meath | |
| Arthur Freke | Clonakilty | |
| Richard Gethin | Newtown Limavady | |
| Sir Thomas Gifford | Trim | |
| John Gilbert | Maryborough | |
| Sir Arthur Gore | County Mayo | |
| Sir William Gore | Banagher | |
| Robert Gorges | Bandonbridge | |
| Isaac Granier | Ennis | |
| Charles Hamilton | County Donegal | |
| Sir Francis Hamilton | County Cavan | |
| Hans Hamilton | County Armagh | |
| William Handcock | County Westmeath | |
| Sir Standish Hartstonge | Limerick City | |
| Francis Harvey | Clonmines | |
| Arthur Hill | County Down | |
| Moyses Hill | Drogheda | |
| Henry Howard | Tallow | By-election May 1661 |
| Sir Henry Ingoldsby | County Clare | |
| John Jeffreys | Antrim Borough | Elected when the constituency was created in 1665 |
| Robert Johnston | Lisburn | Elected 1665 in place of Sir Edward Smith | |
| Oliver Jones | Knocktopher | |
| Oliver Jones | County Roscommon | |
| Sir Theophilus Jones | County Meath | |
| Thomas Keating | Ballynakill | |
| Sir Robert King | Ballyshannon | |
| Sir William King | County Limerick | |
| William Knight | Belfast | |
| Sir Richard Kyrle | Cork City | |
| George Lane | County Roscommon | |
| Sir Richard Lane, 1st Baronet | Tuam | Elected 1665 to replace Robert Ormesby |
| Dr Dudley Loftus | Bannow | |
| Nicholas Loftus | Fethard (County Wexford) | |
| John Lyndon | Killybegs | |
| Boyle Maynard | Youghal | |
| Amos Meredith | Ballynakill | |
| Charles Meredyth | Old Leighlin | |
| Sir Audley Mervyn | County Tyrone | Speaker and Prime Serjeant |
| Henry Mervyn | Augher | |
| Sir Hugh Middleton | Castlebar | Replaced William Rowse, who had been absent without leave |
| Martin Noel | Wexford Borough | |
| Henry O'Brien, Lord Ibrackan | County Clare | |
| Robert Oliver | County Limerick | |
| Sir Richard Osborne | County Waterford | |
| Richard Palfrey | Augher | |
| Sir John Perceval | County Cork | Died 1665 and was replaced by John St Leger. |
| William Petty | Inistioge | |
| Henry Piers | St Johnstown (Co Longford) | |
| Alexander Pigott | Maryborough | |
| John Ponsonby | County Kilkenny | |
| Thomas Pooley | Mallow | |
| John Povey | Swords | |
| Richard Power | County Waterford | Succeeded to peerage 1661 and replaced by James, Lord Annesley |
| John Preston | Navan | |
| Sir Nicholas Purdon | Baltimore | |
| William Purefoy | Ennis | |
| John Read | Bandonbridge | |
| Sir George Rawdon | Carlingford | |
| Robert Reading | Ratoath | Elected 1662 to replace Richard Boughton |
| Sir Richard Reynell | Athboy | |
| Edward Richardson | County Armagh | |
| Sir Oliver St George | County Galway | |
| Sir Heywood St Leger | Mallow | |
| Launcelot Sandes | Dingle | |
| Sir James Shaen | Clonmel | |
| Robert Shapcote | Wicklow Borough | |
| Robert Shapcote | Thomastown | Sat for Wicklow Borough | |
| Sir John Skeffington | County Antrim | |
| Owen Silver | Youghal | |
| Boyle Smith | Tallow | Elected April 1661. Died May 1661. |
| Edward Smith | Lisburn | Resigned in 1665 on appointment as Chief Justice of the Court of Common Pleas (Ireland) |
| Erasmus Smith | Ardee | Replaced John Ruxton, who had been expelled |
| Richard Southwell | Askeaton | |
| Sir Thomas Stanley | County Louth | |
| Alexander Staples | Strabane | Expelled and replaced 1665 by Sir Peter Harvey |
| Richard Stephens | Ardee | Replaced John Chambers, who had been expelled |
| Archibald Stewart | Tallow | By-election May 1661 |
| John Temple | Carlow | Solicitor-General for Ireland. Acted as Speaker, 1661-2, while the previous Speaker, Sir Audley Mervyn was in London. |
| Sir John Temple | County Carlow | |
| Sir William Temple | County Carlow | |
| Sir Henry Tichborne | Sligo Borough | |
| Richard Townsend | Baltimore | |
| Marcus Trevor | County Down | Ennobled 1662 and replaced by Vere Essex Cromwell |
| Sir Henry Tynte | County Cork | Died 1661 and replaced by Sir John Perceval, 1st Baronet. |
| Arthur Upton | Carrickfergus | |
| Nicholas Ward | Downpatrick | |
| Sir James Ware | Dublin University | |
| John Weaver | King's County | |
| William Weldon | Athy | |
| Oliver Wheeler | St Canice | |
| Folliott Wingfield | Tallow | April 1661 - sat for County Wicklow | |
| Folliott Wingfield | County Wicklow | Created Viscount Powerscourt in 1665 |