LDL-receptor-related protein-associated protein

Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Alpha-2-MRAP_N
Alpha-2-MRAP_N
	haddock model of the complex between double module of lrp, cr56, and first domain of receptor associated protein, rap-d1.
Identifiers
Symbol	Alpha-2-MRAP_N
Pfam	PF06400
InterPro	IPR009066
SCOP2	1lre / SCOPe / SUPFAM
Pfam
Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

LRPAP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1LRE, 1NRE, 1OP1, 1OV2, 2FCW, 2FTU, 2FYL, 2P01, 2P03
Identifiers
Aliases	LRPAP1, A2MRAP, A2RAP, HBP44, MRAP, MYP23, RAP, alpha-2-MRAP, LDL-receptor-related protein associated protein, LDL receptor related protein associated protein 1
External IDs	OMIM: 104225; MGI: 96829; HomoloGene: 37612; GeneCards: LRPAP1; OMA:LRPAP1 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	3,532,446 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	35,263,110 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; right auricle of heart; ; right coronary artery; ; apex of heart; ; middle frontal gyrus; ; Descending thoracic aorta; ; putamen; ; caudate nucleus; ; ascending aorta; ; nucleus accumbens;
	Top expressed in
	vestibular membrane of cochlear duct; ; stria vascularis; ; right kidney; ; vestibular sensory epithelium; ; Epithelium of choroid plexus; ; epithelium of lens; ; supraoptic nucleus; ; internal carotid artery; ; external carotid artery; ; human kidney;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	lipase binding; very-low-density lipoprotein particle receptor binding; low-density lipoprotein particle receptor binding; protein binding; signaling receptor binding; heparin binding; receptor antagonist activity; amyloid-beta binding;
Cellular component	cytoplasm; vesicle; cell surface; endoplasmic reticulum; rough endoplasmic reticulum; extracellular region; endosome; endoplasmic reticulum-Golgi intermediate compartment; Golgi apparatus; Golgi lumen; cis-Golgi network; plasma membrane; endosome lumen; rough endoplasmic reticulum lumen;
Biological process	negative regulation of protein binding; negative regulation of very-low-density lipoprotein particle clearance; negative regulation of amyloid-beta clearance; regulation of receptor-mediated endocytosis; extracellular negative regulation of signal transduction; negative regulation of receptor internalization; negative regulation of cell death; amyloid-beta clearance by transcytosis; positive regulation of amyloid-beta clearance; negative regulation of signaling receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	4043
	16976
	ENSG00000163956
	ENSMUSG00000029103
	P30533
	P55302
	NM_002337
	NM_013587
	NP_002328
	NP_038615
	Wikidata
View/Edit Human	View/Edit Mouse

Alpha-2-MRAP_C

solution structure of domain 3 of rap

Identifiers

Symbol

Alpha-2-MRAP_C

Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Low density lipoprotein receptor-related protein-associated protein 1 also known as LRPAP1 or RAP is a chaperone protein which in humans is encoded by the LRPAP1 gene.