LGI1

LGI1
Identifiers
Aliases	LGI1, ADLTE, ADPAEF, ADPEAF, EPITEMPIN, EPT, ETL1, IB1099, leucine-rich, glioma inactivated 1, leucine rich glioma inactivated 1
External IDs	OMIM: 604619; MGI: 1861691; HomoloGene: 3737; GeneCards: LGI1; OMA:LGI1 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	93,806,272 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	38,300,662 bp
RNA expression pattern
	Top expressed in
	Pons; ; Brodmann area 23; ; endothelial cell; ; caudate nucleus; ; putamen; ; middle temporal gyrus; ; Epithelium of choroid plexus; ; nucleus accumbens; ; lateral nuclear group of thalamus; ; superior frontal gyrus;
	Top expressed in
	dentate gyrus; ; dentate gyrus of hippocampal formation granule cell; ; hippocampus proper; ; primary visual cortex; ; temporal lobe; ; Amygdala; ; superior frontal gyrus; ; subdivision of hippocampus; ; subiculum; ; Region I of hippocampus proper;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	signaling receptor binding; protein binding;
Cellular component	extracellular region; cell junction; synapse; extracellular space; membrane; synaptic cleft; glutamatergic synapse;
Biological process	positive regulation of cell growth; cell population proliferation; neuron projection development; positive regulation of synaptic transmission; protein homooligomerization; nervous system development; axon guidance; neurotransmitter receptor localization to postsynaptic specialization membrane;
	Sources:Amigo / QuickGO
Orthologs
	9211
	56839
	ENSG00000108231
	ENSMUSG00000067242
	O95970
	Q9JIA1
	NM_001308275; NM_001308276; NM_005097
	NM_020278
	NP_001295204; NP_001295205; NP_005088
	NP_064674
	Wikidata
View/Edit Human	View/Edit Mouse

Leucine-rich, glioma inactivated 1, also known as LGI1, is a protein which in humans is encoded by the LGI1 gene. It may be a metastasis suppressor.