KIF22

KIF22
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2EDU, 3BFN
Identifiers
Aliases	KIF22, A-328A3.2, KID, KNSL4, OBP, OBP-1, OBP-2, SEMDJL2, kinesin family member 22
External IDs	OMIM: 603213; MGI: 109233; HomoloGene: 32011; GeneCards: KIF22; OMA:KIF22 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	29,805,385 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	126,641,643 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; apex of heart; ; mucosa of transverse colon; ; gonad; ; granulocyte; ; rectum; ; right testis;
	Top expressed in
	human fetus; ; Ileal epithelium; ; fetal liver hematopoietic progenitor cell; ; Paneth cell; ; medial ganglionic eminence; ; tibiofemoral joint; ; primary oocyte; ; primitive streak; ; ureter; ; internal carotid artery;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; nucleotide binding; microtubule binding; ATPase activity; protein binding; ATP binding; microtubule motor activity;
Cellular component	kinesin complex; spindle; chromatin; mitotic spindle; microtubule; cytoskeleton; kinetochore; nucleus; cytoplasm; cytosol; nuclear speck;
Biological process	metaphase plate congression; antigen processing and presentation of exogenous peptide antigen via MHC class II; sister chromatid cohesion; microtubule-based movement; mitotic metaphase plate congression; DNA repair; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	3835
	110033
	ENSG00000079616
	ENSMUSG00000030677
	Q14807
	Q3V300
	NM_001256269; NM_001256270; NM_007317
	NM_145588
	NP_001243198; NP_001243199; NP_015556
	NP_663563; NP_001390552
	Wikidata
View/Edit Human	View/Edit Mouse

Kinesin-like protein KIF22 is a protein that in humans is encoded by the KIF22 gene.

The protein encoded by this gene is a member of kinesin-like protein family. This family of proteins are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests an essential role in metaphase chromosome alignment and maintenance.