KHDRBS1

KHDRBS1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2XA6, 3QHE
Identifiers
Aliases	KHDRBS1, Sam68, p62, p68, KH domain containing, RNA binding, signal transduction associated 1, KH RNA binding domain containing, signal transduction associated 1
External IDs	OMIM: 602489; MGI: 893579; HomoloGene: 4781; GeneCards: KHDRBS1; OMA:KHDRBS1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	32,060,850 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	129,636,096 bp
RNA expression pattern
	Top expressed in
	germinal epithelium; ; ganglionic eminence; ; parietal pleura; ; tendon of biceps brachii; ; visceral pleura; ; ventricular zone; ; superficial temporal artery; ; mucosa of paranasal sinus; ; gingival epithelium; ; lower lobe of lung;
	Top expressed in
	mandibular prominence; ; maxillary prominence; ; ganglionic eminence; ; medial ganglionic eminence; ; somite; ; primitive streak; ; abdominal wall; ; ventricular zone; ; human fetus; ; atrium;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; poly(A) binding; poly(U) RNA binding; SH3 domain binding; protein-containing complex binding; protein binding; RNA binding; nucleic acid binding; protein domain specific binding; identical protein binding;
Cellular component	cytoplasm; Grb2-Sos complex; membrane; nucleus; cytosol; nucleoplasm;
Biological process	regulation of transcription, DNA-templated; regulation of protein stability; transcription, DNA-templated; positive regulation of RNA export from nucleus; cell surface receptor signaling pathway; G2/M transition of mitotic cell cycle; regulation of RNA export from nucleus; cell cycle; cell population proliferation; negative regulation of transcription, DNA-templated; positive regulation of translational initiation; signal transduction; mRNA processing; positive regulation of signal transduction; regulation of mRNA splicing, via spliceosome; spermatogenesis; protein complex oligomerization; regulation of alternative mRNA splicing, via spliceosome; G1/S transition of mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	10657
	20218
	ENSG00000121774
	ENSMUSG00000028790
	Q07666
	Q60749
	NM_001271878; NM_006559
	NM_011317
	NP_001258807; NP_006550
	NP_035447
	Wikidata
View/Edit Human	View/Edit Mouse

KH domain-containing, RNA-binding, signal transduction-associated protein 1 is a protein that in humans is encoded by the KHDRBS1 gene.

This gene encodes a member of the K homology domain-containing, RNA-binding, signal transduction-associated protein family. The encoded protein appears to have many functions and may be involved in a variety of cellular processes, including alternative splicing, cell cycle regulation, RNA 3'-end formation, tumorigenesis, and regulation of human immunodeficiency virus gene expression.