KDM2B

KDM2B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4O64
Identifiers
Aliases	KDM2B, CXXC2, FBXL10, Fbl10, JHDM1B, PCCX2, lysine demethylase 2B
External IDs	OMIM: 609078; MGI: 1354737; HomoloGene: 13069; GeneCards: KDM2B; OMA:KDM2B - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	121,581,023 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	123,127,886 bp
RNA expression pattern
	Top expressed in
	skin of arm; ; mucosa of ileum; ; buccal mucosa cell; ; ganglionic eminence; ; ventricular zone; ; cerebellar vermis; ; thymus; ; epithelium of nasopharynx; ; monocyte; ; tibialis anterior muscle;
	Top expressed in
	zygote; ; ganglionic eminence; ; primary oocyte; ; secondary oocyte; ; spermatocyte; ; morula; ; spermatid; ; Mesencephalon; ; epiblast; ; neural tube;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; rRNA binding; zinc ion binding; dioxygenase activity; metal ion binding; histone demethylase activity; protein binding; histone H3-methyl-lysine-36 demethylase activity; RNA binding; oxidoreductase activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding;
Cellular component	nucleoplasm; nucleolus; PcG protein complex; nucleus; chromosome;
Biological process	negative regulation of neuron apoptotic process; midbrain-hindbrain boundary morphogenesis; regulation of transcription, DNA-templated; lateral ventricle development; histone H2A monoubiquitination; negative regulation of neural precursor cell proliferation; hindbrain development; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; third ventricle development; positive regulation of cell growth; embryonic camera-type eye morphogenesis; histone H3-K36 demethylation; spermatogenesis; forebrain development; positive regulation of stem cell population maintenance; initiation of neural tube closure; midbrain development; fourth ventricle development; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	84678
	30841
	ENSG00000089094
	ENSMUSG00000029475
	Q8NHM5
	Q6P1G2
	NM_001005366; NM_032590
NM_001003953; NM_001005866; NM_013910; NM_001378863; NM_001378864;
	NM_001378865
	NP_001005366; NP_115979
	NP_001003953; NP_038938; NP_001365792; NP_001365793; NP_001365794
	Wikidata
View/Edit Human	View/Edit Mouse

The human KDM2B gene encodes the protein lysine (K)-specific demethylase 2B.