KCNU1

KCNU1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4HPF
Identifiers
Aliases	KCNU1, KCNMC1, KCa5, KCa5.1, Kcnma3, Slo3, potassium calcium-activated channel subfamily U member 1
External IDs	OMIM: 615215; MGI: 1202300; HomoloGene: 7392; GeneCards: KCNU1; OMA:KCNU1 - orthologs
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	26,427,967 bp
RNA expression pattern
	Top expressed in
	sperm; ; bone marrow cells; ; caput epididymis; ; substantia nigra; ; monocyte; ; mammary gland; ; female breast; ; subcutaneous adipose tissue; ; male reproductive gland; ; prostate;
	Top expressed in
	spermatid; ; morula; ; lumbar spinal ganglion; ; seminiferous tubule; ; spermatocyte; ; facial motor nucleus; ; blastocyst; ; islet of Langerhans; ; embryo; ; anterior horn of spinal cord;
	More reference expression data
	n/a
Gene ontology
Molecular function	voltage-gated potassium channel activity; large conductance calcium-activated potassium channel activity; ion channel activity; potassium channel activity; voltage-gated ion channel activity; calcium-activated potassium channel activity; outward rectifier potassium channel activity;
Cellular component	integral component of membrane; voltage-gated potassium channel complex; plasma membrane; membrane;
Biological process	potassium ion transport; regulation of ion transmembrane transport; ion transport; transmembrane transport; potassium ion transmembrane transport; sperm-egg recognition; reproductive process; regulation of membrane potential;
	Sources:Amigo / QuickGO
Orthologs
	157855
	16532
	n/a
	ENSMUSG00000031576
	A8MYU2
	O54982
	NM_001031836
	NM_008432
	NP_001027006
	NP_032458
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium channel, subfamily U, member 1, also known as KCNU1, is a gene encoding the K_Ca5.1 protein.

Although this channel is structurally related to the calcium-activated potassium channels, it cannot be classified as such since it is activated by high intracellular pH and relatively insensitive to changes in calcium concentrations.