KCNA5

KCNA5
Identifiers
Aliases	KCNA5, ATFB7, HCK1, HK2, HPCN1, KV1.5, PCN1, potassium voltage-gated channel subfamily A member 5
External IDs	OMIM: 176267; MGI: 96662; HomoloGene: 1683; GeneCards: KCNA5; OMA:KCNA5 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	5,046,788 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	126,512,375 bp
RNA expression pattern
	Top expressed in
	cardiac muscle tissue of right atrium; ; right auricle of heart; ; right coronary artery; ; popliteal artery; ; tibial arteries; ; testicle; ; Epithelium of choroid plexus; ; ascending aorta; ; left coronary artery; ; Descending thoracic aorta;
	Top expressed in
	olfactory epithelium; ; epithelium of lens; ; trigeminal nerve; ; retina; ; endocardial cushion; ; olfactory tubercle; ; neural layer of retina; ; renal pelvis; ; nucleus accumbens; ; myocardium of ventricle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	potassium channel inhibitor activity; outward rectifier potassium channel activity; potassium channel activity; scaffold protein binding; voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization; voltage-gated potassium channel activity involved in SA node cell action potential repolarization; delayed rectifier potassium channel activity; voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization; voltage-gated ion channel activity; ion channel activity; protein binding; alpha-actinin binding; voltage-gated potassium channel activity; signaling receptor binding; protein kinase binding;
Cellular component	integral component of membrane; Golgi apparatus; membrane; intercalated disc; intracellular canaliculus; voltage-gated potassium channel complex; plasma membrane; integral component of plasma membrane; potassium channel complex; Z discdkac; endoplasmic reticulum; perinuclear region of cytoplasm; caveola; membrane raft; cell surface;
Biological process	Notch signaling pathway; regulation of atrial cardiac muscle cell membrane repolarization; positive regulation of myoblast proliferation; regulation of potassium ion transport; response to hypoxia; membrane hyperpolarization; regulation of insulin secretion; response to hyperoxia; regulation of membrane potential; regulation of ion transmembrane transport; response to mechanical stimulus; ion transport; response to organic substance; membrane repolarization during bundle of His cell action potential; positive regulation of G1/S transition of mitotic cell cycle; potassium ion transport; regulation of vasoconstriction; potassium ion homeostasis; protein complex oligomerization; transmembrane transport; potassium ion transmembrane transport; negative regulation of potassium ion transport; atrial cardiac muscle cell action potential; membrane repolarization during SA node cell action potential; regulation of heart rate by cardiac conduction; protein homooligomerization; response to hydrogen peroxide; negative regulation of cytosolic calcium ion concentration; membrane repolarization during atrial cardiac muscle cell action potential; regulation of molecular function; transport; potassium ion export across plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	3741
	16493
	ENSG00000130037
	ENSMUSG00000045534
	P22460
	Q61762
	NM_002234
	NM_145983
	NP_002225
	NP_666095
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium voltage-gated channel, shaker-related subfamily, member 5, also known as KCNA5 or K_v1.5, is a protein that in humans is encoded by the KCNA5 gene.