KAT8

KAT8
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2GIV, 2PQ8, 2Y0M, 3QAH, 3TOA, 3TOB, 4DNC
Identifiers
Aliases	KAT8, MOF, MYST1, ZC2HC8, hMOF, lysine acetyltransferase 8, LIGOWS
External IDs	OMIM: 609912; MGI: 1915023; HomoloGene: 41676; GeneCards: KAT8; OMA:KAT8 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	31,131,393 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	127,525,009 bp
RNA expression pattern
	Top expressed in
	cerebellar hemisphere; ; right hemisphere of cerebellum; ; right ovary; ; left ovary; ; corpus epididymis; ; cerebellar vermis; ; paraflocculus of cerebellum; ; left uterine tube; ; external globus pallidus; ; apex of heart;
	Top expressed in
	seminiferous tubule; ; spermatocyte; ; spermatid; ; primary oocyte; ; neural layer of retina; ; hand; ; muscle of thigh; ; otolith organ; ; tail of embryo; ; utricle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; transcription factor binding; metal ion binding; histone acetyltransferase activity (H4-K8 specific); histone acetyltransferase activity; histone acetyltransferase activity (H4-K5 specific); methylated histone binding; protein binding; histone acetyltransferase activity (H4-K16 specific); enzyme binding; acetyltransferase activity; acyltransferase activity; histone binding;
Cellular component	nucleoplasm; chromosome; MLL1 complex; histone acetyltransferase complex; nucleus; kinetochore; MSL complex; nuclear matrix;
Biological process	myeloid cell differentiation; regulation of transcription, DNA-templated; transcription, DNA-templated; histone H4-K5 acetylation; positive regulation of transcription, DNA-templated; regulation of autophagy; histone H4-K16 acetylation; negative regulation of transcription, DNA-templated; histone H4-K8 acetylation; histone acetylation; chromatin organization; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	84148
	67773
	ENSG00000103510
	ENSMUSG00000030801
	Q9H7Z6
	Q9D1P2
	NM_032188; NM_182958
	NM_026370; NM_001360699
	NP_115564; NP_892003
	NP_080646; NP_001347628
	Wikidata
View/Edit Human	View/Edit Mouse

K(lysine) acetyltransferase 8 (KAT8) is an enzyme that in humans is encoded by the KAT8 gene.