JMJD6

JMJD6
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3K2O, 3LD8, 3LDB
Identifiers
Aliases	JMJD6, PSR, PTDSR, PTDSR1, arginine demethylase and lysine hydroxylase, jumonji domain containing 6, arginine demethylase and lysine hydroxylase
External IDs	OMIM: 604914; MGI: 1858910; HomoloGene: 9046; GeneCards: JMJD6; OMA:JMJD6 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	76,726,799 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	116,734,275 bp
RNA expression pattern
	Top expressed in
	saphenous vein; ; vena cava; ; gastric mucosa; ; muscle layer of sigmoid colon; ; trachea; ; pericardium; ; popliteal artery; ; tibial arteries; ; right auricle of heart; ; anterior pituitary;
	Top expressed in
	otic vesicle; ; otic placode; ; saccule; ; yolk sac; ; epiblast; ; morula; ; zygote; ; embryo; ; embryo; ; granulocyte;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	iron ion binding; protein homodimerization activity; dioxygenase activity; metal ion binding; histone H3-methyl-arginine-2 demethylase activity; protein binding; histone H3-methyl-arginine-3 demethylase activity; single-stranded RNA binding; RNA binding; identical protein binding; oxidoreductase activity; peptidyl-lysine 5-dioxygenase activity; histone demethylase activity; signaling receptor activity; transcription coactivator activity; demethylase activity; oxidative RNA demethylase activity; P-TEFb complex binding;
Cellular component	cytosol; plasma membrane; nucleoplasm; nucleolus; nucleus; ribonucleoprotein complex; cytoplasm;
Biological process	recognition of apoptotic cell; cell differentiation; regulation of transcription, DNA-templated; T cell differentiation in thymus; kidney development; lung development; histone H3-R2 demethylation; mRNA processing; sprouting angiogenesis; regulation of mRNA splicing, via spliceosome; transcription, DNA-templated; histone H4-R3 demethylation; multicellular organism development; apoptotic cell clearance; heart development; cell surface receptor signaling pathway; blood vessel development; retina development in camera-type eye; RNA splicing; macrophage activation; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine; erythrocyte development; chromatin organization; positive regulation of transcription, DNA-templated; protein demethylation; oxidative RNA demethylation; positive regulation of transcription by RNA polymerase II; protein homooligomerization;
	Sources:Amigo / QuickGO
Orthologs
	23210
	107817
	ENSG00000070495
	ENSMUSG00000056962
	Q6NYC1
	Q9ERI5
	NM_001081461; NM_015167
	NM_033398; NM_001363363
	NP_001074930; NP_055982
	NP_203971; NP_001350292
	Wikidata
View/Edit Human	View/Edit Mouse

Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 is an enzyme that in humans is encoded by the JMJD6 gene.