Isothiazole
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| Names | |||
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| Preferred IUPAC name
1,2-Thiazole | |||
| Other names
isothiazole | |||
| Identifiers | |||
3D model (JSmol) |
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| ChEBI | |||
| ChemSpider | |||
| ECHA InfoCard | 100.241.294 | ||
PubChem CID |
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CompTox Dashboard (EPA) |
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| Properties | |||
| C3H3NS | |||
| Molar mass | 85.12 g·mol−1 | ||
| Boiling point | 114 °C (237 °F; 387 K) | ||
| Acidity (pKa) | −0.5 (of conjugate acid) | ||
| Related compounds | |||
Related compounds |
thiazole, isoxazole | ||
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references | |||
Isothiazole, or 1,2-thiazole, is an organic compound consisting with the formula (CH)3S(N). The ring is unsaturated and features an S-N bond. The isomeric thiazole, where the S and N are not directly bonded are far more common.
Isothiazones are produced by oxidation of enamine-thiones. The ring structure of isothiazole is incorporated into larger compounds with biological activity such as the pharmaceutical drugs ziprasidone and perospirone.