Isothiazole

Isothiazole
Names
Preferred IUPAC name
1,2-Thiazole
Other names
isothiazole
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.241.294
UNII
  • InChI=1S/C3H3NS/c1-2-4-5-3-1/h1-3H Y
    Key: ZLTPDFXIESTBQG-UHFFFAOYSA-N Y
  • InChI=1/C3H3NS/c1-2-4-5-3-1/h1-3H
    Key: ZLTPDFXIESTBQG-UHFFFAOYAS
  • n1sccc1
Properties
C3H3NS
Molar mass 85.12 g·mol−1
Boiling point 114 °C (237 °F; 387 K)
Acidity (pKa) −0.5 (of conjugate acid)
Related compounds
Related compounds
thiazole, isoxazole
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is YN ?)
Infobox references

Isothiazole, or 1,2-thiazole, is an organic compound consisting with the formula (CH)3S(N). The ring is unsaturated and features an S-N bond. The isomeric thiazole, where the S and N are not directly bonded are far more common.

Isothiazones are produced by oxidation of enamine-thiones. The ring structure of isothiazole is incorporated into larger compounds with biological activity such as the pharmaceutical drugs ziprasidone and perospirone.