Iran–United States relations during the Biden administration

Iran–United States relations during the Biden administration (2021–2025) were shaped by efforts to revive the 2015 nuclear agreement alongside ongoing regional tensions, sanctions, cyberattacks, and proxy conflicts. Early in Joe Biden’s presidency, U.S. officials expressed interest in returning to the Joint Comprehensive Plan of Action (JCPOA), but negotiations in Vienna eventually stalled. Iran increased uranium enrichment and imposed retaliatory sanctions, while the U.S. imposed new sanctions over missile programs, oil exports, and human rights abuses.

Tensions persisted throughout this era, marked by recurring proxy attacks on U.S. bases, which intensified following the outbreak of the Gaza war in late 2023, and by subsequent American retaliatory strikes. The period also saw disputes over the assassination of Qasem Soleimani, and military escalations across the Gulf region. In 2023, a breakthrough occurred with a U.S.–Iran prisoner swap and the release of frozen Iranian funds, though indirect diplomacy remained fragile. Iran was later accused of interfering in the 2024 U.S. presidential election through cyber operations and AI disinformation. Alleged assassination plots targeting Donald Trump and dissidents on U.S. soil further strained relations. By late 2024, relations remained adversarial, marked by unresolved security disputes and growing mistrust.