Indigo carmine

Indigotindisulfonate sodium
Clinical data
Trade names	Bludigo
License data	US DailyMed: Indigotindisulfonate;
Identifiers
E number	E132 (colours)
CompTox Dashboard (EPA)	DTXSID1020190 ;
ECHA InfoCard	100.011.572

Indigo carmine
Names
	Preferred IUPAC name Disodium [2(2′)E]-3,3′-dioxo-1,1′,3,3′-tetrahydro[2,2′-biindolylidene]-5,5′-disulfonate
	Other names indigotine; 5,5′-indigodisulfonic acid sodium salt; Brilliant Indigo; 4 G; C.I. Acid Blue 74; C.I. 73015; CI Food Blue 1; FD&C Blue 2; Sicovit Indigotin 85; E132; indigotindisulfonate sodium;
Identifiers
CAS Number	860-22-0 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:31695 ;
ChEMBL	ChEMBL2105023;
ChemSpider	4447431 ;
DrugBank	DB11577; DBSALT001752;
ECHA InfoCard	100.011.572
EC Number	212-728-8;
E number	E132 (colours)
KEGG	D01563;
PubChem CID	2723854;
UNII	D3741U8K7L ;
CompTox Dashboard (EPA)	DTXSID1020190 ;
	InChI InChI=1S/C16H10N2O8S2.2Na/c19-15-9-5-7(27(21,22)23)1-3-11(9)17-13(15)14-16(20)10-6-8(28(24,25)26)2-4-12(10)18-14;;/h1-6,17-18H,(H,21,22,23)(H,24,25,26);;/q;2+1/p-2/b14-13+;; Key: KHLVKKOJDHCJMG-QDBORUFSSA-L ; InChI=1/C16H10N2O8S2.2Na/c19-15-9-5-7(27(21,22)23)1-3-11(9)17-13(15)14-16(20)10-6-8(28(24,25)26)2-4-12(10)18-14;;/h1-6,17-18H,(H,21,22,23)(H,24,25,26);;/q;2+1/p-2/b14-13+;; Key: KHLVKKOJDHCJMG-AKPRSONXBD;
	SMILES [Na+].[Na+].[O-]S(=O)(=O)c3cc4C(=O)\C(=C2\C(=O)c1cc(ccc1N2)S([O-])(=O)=O)Nc4cc3;
Properties
Chemical formula	C16H8N2Na2O8S2
Molar mass	466.36 g/mol
Appearance	purple solid
Melting point	>300 °C (572 °F)
Solubility in water	10 g/L (25 °C (77 °F))
Hazards
	GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H302
NFPA 704 (fire diamond)	2 1 0
Pharmacology
ATC code	V04CH02 (WHO)
Legal status	US: ℞-only;
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Indigo carmine, or 5,5′-indigodisulfonic acid sodium salt, is an organic salt derived from indigo by aromatic sulfonation, which renders the compound soluble in water. Like indigo, it produces a blue color, and is used in food and other consumables, cosmetics, and as a medical contrast agent and staining agent; it also acts as a pH indicator. It is approved for human consumption in the United States and European Union. It has the E number E132, and is named Blue No. 2 by the US Federal Food, Drug, and Cosmetic Act.

Names


Preferred IUPAC name Disodium [2(2′)E]-3,3′-dioxo-1,1′,3,3′-tetrahydro[2,2′-biindolylidene]-5,5′-disulfonate
Other names indigotine 5,5′-indigodisulfonic acid sodium salt Brilliant Indigo 4 G C.I. Acid Blue 74 C.I. 73015 CI Food Blue 1 FD&C Blue 2 Sicovit Indigotin 85 E132 indigotindisulfonate sodium
Identifiers
CAS Number	860-22-0^Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:31695^N
ChEMBL	ChEMBL2105023
ChemSpider	4447431^Y
DrugBank	DB11577 DBSALT001752
ECHA InfoCard	100.011.572
EC Number	212-728-8
E number	E132 (colours)
KEGG	D01563
PubChem CID	2723854
UNII	D3741U8K7L^Y
CompTox Dashboard (EPA)	DTXSID1020190
InChI InChI=1S/C16H10N2O8S2.2Na/c19-15-9-5-7(27(21,22)23)1-3-11(9)17-13(15)14-16(20)10-6-8(28(24,25)26)2-4-12(10)18-14;;/h1-6,17-18H,(H,21,22,23)(H,24,25,26);;/q;2+1/p-2/b14-13+;;^Y Key: KHLVKKOJDHCJMG-QDBORUFSSA-L^Y InChI=1/C16H10N2O8S2.2Na/c19-15-9-5-7(27(21,22)23)1-3-11(9)17-13(15)14-16(20)10-6-8(28(24,25)26)2-4-12(10)18-14;;/h1-6,17-18H,(H,21,22,23)(H,24,25,26);;/q;2+1/p-2/b14-13+;; Key: KHLVKKOJDHCJMG-AKPRSONXBD
SMILES [Na+].[Na+].[O-]S(=O)(=O)c3cc4C(=O)\C(=C2\C(=O)c1cc(ccc1N2)S([O-])(=O)=O)Nc4cc3
Properties
Chemical formula	C₁₆H₈N₂Na₂O₈S₂
Molar mass	466.36 g/mol
Appearance	purple solid
Melting point	>300 °C (572 °F)
Solubility in water	10 g/L (25 °C (77 °F))
Hazards
GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H302
NFPA 704 (fire diamond)	2 1 0
Pharmacology
ATC code	V04CH02 (WHO)
Legal status	US: ℞-only
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references